Search results for "multinucleated giant cells"

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Small-sized granules of biphasic bone substitutes support fast implant bed vascularization

2015

The present study investigated the influence of granule size of 2 biphasic bone substitutes (BoneCeramic® 400-700 μm and 500-1000 μm) on the induction of multinucleated giant cells (MNGCs) and implant bed vascularization in a subcutaneous implantation model in rats. Furthermore, degradation mechanisms and particle phagocytosis of both materials were examined by transmission electron microscopy (TEM). Both granule types induced tissue reactions involving primarily mononuclear cells and only small numbers of MNGCs. Higher numbers of MNGCs were detected in the group with small granules starting on day 30, while higher vascularization was observed only at day 10 in this group. TEM analysis reve…

Foreign-body giant cellPathologymedicine.medical_specialtyMaterials sciencebiphasic bone substitutePhagocytosisBiomedical EngineeringNeovascularization PhysiologicMedicine (miscellaneous)Giant CellsPeripheral blood mononuclear cellBone and BonesBiomaterialsMiceMultinucleatevascularizationMaterials TestingmedicineAnimalsParticle SizedegradationGranule (cell biology)granule sizephagocytosisGeneral MedicineRatsCell biologyDisease Models AnimalTransmission electron microscopyGiant cellBone SubstitutesLeukocytes MononuclearMicroscopy Electron ScanningBoneCeramicFemaleHydroxyapatitesImplantmultinucleated giant cellsResearch PaperBiomatter

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